Doug Atchison

Physician (Nephrology, Internal Medicine), University of Michigan Health System

Education: BS Michigan State University, Human Biology
Graduate Program Affiliation: Physiology
Research Interests: Hypertension
Clinical Interests: Undecided
Advisor: William Beierwaltes, Physiology (Henry Ford Health Systems)

Publications/Presentations:

1. The Influence of extracellular and intracellular calcium on the secretion of renin. Atchison DK, Beierwaltes WH. Pflugers Arch. 2013 Jan;465(1):59-69. doi: 10.1007/s00424-012-1107-x. Epub 2012 Apr 28.
2. Hypercalcemia reduces plasma renin via Parathyroid hormone, renal interstitial calcium, and the calcium-sensing receptor. Atchison DK, Harding P, Beierwaltes WH. Hypertension 2011 Oct: 58(4):604-610. Epub 2011 Aug 8.
3. Acute activation of the calcium-sensing receptor inhibits plasma renin activity in vivo. Atchison DK, Ortiz-Capisano MC, Beierwaltes WH. Am J Physiol Regul Integr Comp Physiol. 2010 Oct; 299(4):R1020-6. Epub 2010 Jul 21.
4. Parathyroid hormone stimulates juxtaglomerular cell cAMP accumulation without stimulating renin release. Atchison DK, Harding P, Cecilia Ortiz-Capisano M, Peterson EL, Beierwaltes WH. Am J Physiol Renal Phyiol. 2012 Oct 15;p 303(8):F1157-65. Epub 2012 Aug. 15.
5. Parathyroid hormone-related protein stimulates plasma renin activity via its anorexic effects on sodium chloride intake. Atchison DK, Westrick E, Szandzik DL, Gordish KL, Beierwaltes WH. Am J Physiol Endocrinol Metab. 2012 Aug; 303(4); E457-63.
6. Adenosine inhibits renin release from juxtaglomerular cells via an A1 Receptor TRPC-mediated pathway. Ortiz-Capisano MC, Atchison DK, Harding P, Lasley RD, Beierwalted WH. Am J Physiol Renal Physiol. 2013 Jul 24.
7. Anandamide inhibits transport-related oxygenconsumption in the loop of Henle by activating CB1 receptors. Silva GB, Atchison DK, Juncos LI, Garcia NH. Am J Physiol Renal Physiol. 2013 Feb15;304(4):F376-81. Epub 2012 Dec 5.
8. Calcium-Sensing Receptor Activation In Vivo Decreases Plasma Renin Activity. Atchison DK, Beierwaltes WH. FASEB J. 22:3127, D496. Experimental Biology, New Orleans, LA, 2009.
9. Calcium-inhibitable isoforms of adenylyl cyclase are not expressed in rat parathyroid. Atchison DK, Harding P, Beierwaltes WH. FASEB J. 21(S): 40: A39, 343. Experimental Biology, Washington DC, 2007.
10. Effects of Lead on L-Type Voltage-Gated Calcium Channel Function in Smooth Muscle Cells. Atchison D.D., Cobbett P.J., Hajela R.K., Fink G.D., Atchison W.D. Abstract published at the Annual Meeting for The Society of Toxicology. March, 2006.
11. Effects of Activation and Inhibition of Group I Metabotropic Glutamate Receptor Subtype 1 in Methylmercury-Induced Ca2 Dysregulation in Cerebellar Granule Cells in Rats. Segarra A., Atchison D.K., Atchison W.D. Abstract published at the Annual Meeting for The Society of Toxicology. March 2006.
12. Effects of GABA-B Receptor Activation & Inhibition on Methylmercury-induced alterations of intracellular Ca in Rat cerebellar granule neurons. D.K. Atchison, W.D. Atchison. Abstract published at the Annual Meeting for The Society of Toxicology. March, 2005.

Posters:

1. Calcium-inhibitable isoforms of adenylyl cyclase are not expressed in rat parathyroid. Poster presented at 2007 FASEB meeting.

Awards:

1. Medical Student Research Day presentations 2007 and 2008
2. MD PhD presentation day 2007 and 2008

Grants/Fellowships: 5 year NIH F30 Fellowship award 2009

Outside Interests: Sanchin-Ryu, working out, food

Favorite Aspects of the MD PhD Program: In addition to research that interested me, I wanted a place that gave a strong clinical education as well