Christopher McHugh
Resident, Ophthalmology-Head and Neck Surgery (PGY4), Harvard Medical School, Boston, MA
Education: B.S. in Biochemistry, University of Michigan-Ann Arbor
Graduate Program Affiliation: Cancer Biology
Research Interests: Utilizing PET imaging to monitor response to chemotherapy
Advisor: Anthony Shields, M.D., Ph.D, Cancer Biology
Publications/Presentations:
McHugh CI, Thipparthi M, Polin L, Lawhorn-Crews JM, Gadgeel S, Akoury J, Patki M, Douglas KA, Mangner TJ, Li J, Matherly LH, Ratnam M, Shields AF: A translational model utilizing radiolabeled FLT with PET to monitor the effect of dexamethasone on non-small cell lung cancer. J Nucl Med. 2018 Apr 19 [Epub ahead of print]
McHugh CI, Lawhorn-Crews JM, Douglas KA, Modi D, Jones SK, Mangner TJ, Collins JM, Shields AF: Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents: 18F-FAU, 18F-FMAU, and 18F-FLT. Cancer Imaging. 2016;16(1):34.
Li J, Kim S, Shields AF, Douglas KA, McHugh CI, Lawhorn-Crews JM, Wu J, Mangner TJ, LoRusso PM: Integrating Dynamic Positron Emission Tomography and Conventional Pharmacokinetic Studies to Delineate Plasma and Tumor Pharmacokinetics of FAU, a Prodrug Bioactivated by Thymidylate Synthase. J Clin Pharmacol. 2016;56(11):1433-1447.
McHugh CI, Shields A: FLT-PET Evaluation of Radiation Response. J Nucl Med. 2015;56(6):813-4.
Awards:
2012 – 2013 – Prentis Foundation Medical Scholarship, Detroit, MI
2013 – Alpha Omega Alpha Medical Honor Society Inductee
2015 – 2016 – DeRoy Testamentary Foundation Research Fellowship
2016 – 2018 – O. B. Weed Merit Scholarship, Detroit, MI
Conferences Attended:
McHugh CI, Lawhorn-Crews J, Douglas K, Modi D, Mangner T, Shields A: The Effect of Capecitabine Treatment on the Uptake of Fluoropyrimidine Tracers: FLT, FMAU, and FAU. LBAP 045, World Molecular Imaging Society Annual Congress, Seoul, South Korea, September 20, 2014
McHugh CI, Lawhorn-Crews J, Gadgeel S, Patki M, Mangner T, Matherly LH, Ratnam M, Shields A: Utilizing 18F-FLT to Monitor the Effect of Dexamethasone on NSCLC. LBAP 074, World Molecular Imaging Society Annual Congress, Honolulu, Hawaii, September 3, 2015
Funding:
2013 – 2016 Wayne State Graduate Research Assistantship, Detroit, MI
2015 – 2016 DeRoy Testamentary Foundation Research Fellowship, Detroit, MI
Residency Match: Otolaryngology, Harvard Medical School / Massachusetts Eye and Ear
Other Interests: Travel, NBA basketball, Running and Classic Rock