Biography

Education: B.A. Integrative Biology, Skidmore College, Saratoga Springs, NY
Year in Program: G1
Thesis Mentor: J. Richard Pilsner, PhD, MPH

Research Interests

My research focuses on impacts of sperm epigenetic aging, sperm DNA methylation variability, and environmental exposures on male fertility and reproductive outcomes.

Honors and Awards

• 2017 Departmental Honors, Skidmore College Department of Biology
• 2015 Barry Goldwater Scholarship Honorable Mention
• 2015 Second Place, Scientific Poster Session, University of Massachusetts Medical School Summer Research Fellowship Program
• 2015 SEE-Beyond Award, Skidmore College

Publications

• Sawant, S., Oluwayiose, O.A., Nowak, K., Maxwell, D.L., Houle, E., Paskavitz, A.L., Saddiki, H., Bertolla, R.P., & Pilsner, J.R. Associations Between Sperm Epigenetic Age and Semen Parameters. Current Issues in Molecular Biology. 2024. Under review.
• Guo, R., Qi, H., Amyar, A., Cai, X., Kucukseymen, S., Haji-Valizadeh, H., Rodriguez, J., Paskavitz, A., Pierce, P., Goddu, B., Thompson, R.B., & Nezafat, R. Quantification of changes in myocardial T1* values with exercise cardiac MRI using a free-breathing non-electrocardiograph radial imaging. Magnetic Resonance in Medicine. 2022, 1-14. https://doi.org/10.1002/mrm.29346
• Haji-Valizadeh, H., Guo, R., Kucukseymen, S., Tuyen, Y., Rodriguez, J., Paskavitz, A., Pierce, P., Goddu, B., Ngo, L.H., Nezafat, R. Comparison of Complex k-Space Data and Magnitude-Only for Training of Deep Learning-Based Artifact Suppression for Real-Time Cine MRI. Frontiers in Physics. 2021, 9:684184. https://www.frontiersin.org/journals/physics/articles/10.3389/fphy.2021.684184/full
• Haji-Valizadeh, H., Guo, R., Kucukseymen, S., Paskavitz, A., Cai, X., Rodriguez, J., Pierce, P., Goddu, B., Kim, D., Manning, W., Nezafat, R. Highly accelerated free-breathing real-time phase contrast cardiovascular MRI via complex-difference deep learning. Magnetic Resonance in Medicine. 2021, 86(2), 804-819. https://doi.org/10.1002/mrm.28750
• Guo, R., Cai, X., Kucukseymen, S., Rodriguez, J., Paskavitz, A., Pierce, P., Goddu, B., & Nezafat, R. Free-breathing whole-heart multi-slice myocardial T1 mapping in 2 minutes. Magnetic Resonance in Medicine. 2021, 85(1):89-102. https://doi.org/10.1002/mrm.28402
• Guo, R., Cai, X., Kucukseymen, S., Rodriguez, J., Paskavitz, A., Pierce, P., Goddu, B., Thompson, R.B., Nezafat, R. Free-breathing simultaneous myocardial T1 and T2 mapping with whole left ventricle coverage. Magnetic Resonance in Medicine. 2021;85(3):1308-1321. https://doi.org/10.1002/mrm.28506
• Csecs, I., Pashakhanloo, F., Paskavitz, A., Jang, J., Al-Otaibi, T., Neisius, U., Manning, W.J., & Nezafat, R. Association Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy. Journal of the American Heart Association. 2020, 9(19). https://pubmed.ncbi.nlm.nih.gov/33006296/
• Breves, J.P., Springer-Miller, R.H., Chenoweth, D.A., Paskavitz, A.L., Chang, A.Y.H., Regish, A.M., Einarsdottir, I.E., Björnsson, B.Th., & McCormick, S.D. Cortisol regulates insulin-like growth-factor binding protein (igfbp) gene expression in Atlantic salmon parr. Molecular and Cellular Endocrinology. 2020, 518, 110989. https://doi.org/10.1016/j.mce.2020.110989
• El-Rewaidy, H., Neisius, U., Mancio, J., Kucukseymen, S., Rodriguez, J., Paskavitz, A., Menze, B., & Nezafat, R. Deep complex convolutional network for fast reconstruction of 3D late gadolinium enhancement cardiac MRI. NMR in Biomedicine. 2020, 33(7), e4312. https://doi.org/10.1002/nbm.4312
• Gordon, S., Xiao, Y., Paskavitz, A.L., Navarro-Tito, N., Navea, J.G., & Padilla-Benavides, T. Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells. Journal of Visualized Experiments. 2019, 147, e59519. https://doi.org/10.3791/59519
• Paskavitz, A.L., Quintana, J., Cangussu, D., Tavera-Montañez, C., Xiao, Y., Ortiz-Miranda, S., Navea, J.G., & Padilla-Benavides, T. Differential expression of zinc transporters accompanies the differentiation of C2C12 myoblasts. Journal of Trace Elements in Medicine and Biology. 2018, 49, 27–34. https://doi.org/10.1016/j.jtemb.2018.04.024
• Vest, K. E., Paskavitz, A.L., Lee, J.B., & Padilla-Benavides, T. Dynamic changes in copper homeostasis and post transcriptional regulation of Atp7a during myogenic differentiation. Metallomics. 2018,10(2), 309–322. https://pubmed.ncbi.nlm.nih.gov/29333545/
•  Padilla-Benavides, T., Nasipak, B.T., Paskavitz, A.L., Haokip, D.T., Schnabl, J.M., Nickerson, J.A., & Imbalzano, A.N. Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition. The Journal of Biological Chemistry. 2017, 292(45), 18592–18607. https://doi.org/10.1074/jbc.M117.799676
• Samuchiwal, S.K., Balestrieri, B., Paskavitz, A., Raff, H., & Boyce, J.A. Endogenous PGE2 Amplifies IL-33 Production By Macrophages through an EP2/EP4-cAMP-Epac-Dependent Pathway. The Journal of Allergy and Clinical Immunology. 2017, 139, 2. https://doi.org/10.1016/j.jaci.2016.12.854 [abstract only]
• Borgatta, J., Paskavitz, A., Kim, D., & Navea, J.G. Comparative evaluation of iron leach from fly ash from different source regions under atmospherically relevant conditions. Environmental Chemistry. 2016, 13, 4. https://doi.org/10.1071/EN16046

 

Other Information

Conferences:

• 2024 American Society of Andrology Annual Meeting, Denver, CO
• 2024 Graduate Research Symposium, Wayne State University, Detroit, MI
• 27th Annual Chuan-Pu Lee, PhD Endowed Graduate Student Research Presentation Day, Wayne State University School of Medicine, Detroit, MI
• SACNAS New England Regional Conference, Tufts University School of Medicine, Boston, MA. 2017.
• Summer Research Fellowship Program Scientific Poster Session. University of Massachusetts Medical School, Worcester, MA. 2015.
• American Chemical Society National Meeting and Exposition. Denver, CO. 2015.
• New York Six Liberal Arts Consortium Upstate New York Undergraduate Research Conference. Hobart and William Smith Colleges, Geneva, NY. 2014

Anything else you would like on your profile that the above material does not cover:

Student organization leadership positions:

• Executive MD/PhD Representative, WSUSOM Student Senate
• Lead Organizer and Advisor, WSUSOM Graduate Student Senate
• Senior Garden Manager, Medical Student Garden

Personal interests: dance, scuba diving, hiking

 

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