Jenna Carter

Jenna Carter

Jenna Carter


Education: Michigan State University (Lyman Briggs Residential Science College), B.S.
Year in Program: M4
Thesis Mentor: Dr. Yubin Ge, PhD, Cancer Biology Program

Funding: DeRoy Testamentary Fellowship Award

Conferences Attended

American Association of Cancer Research (AACR) Annual Conference
American Association of Medical College (AAMC) Annual Conference
Cancer Biology Student Research Symposium
Karmanos Cancer Institute (KCI) Trainee Research Annual Retreat
National MD/PhD Student Research Conference
Tumor Biology and Microenvironment Annual Retreat
WSU Graduate and Post-Doctoral Research Symposium
WSUSOM Medical Education Research and Innovation (MERI) Annual Conference


Research Interests

Investigating novel approaches to targeting therapy resistance in acute myeloid leukemia (AML) through targeting mitochondrial function and cellular metabolism.

Honors and Awards

2022-2023 – DeRoy Testamentary Fellowship Award
2019-2022 – Rumble Fellowship Award
2017-2019 – Board of Governors Full Tuition Scholarship, Wayne State University School of Medicine
2015 – Graduated with Honors, Lyman Briggs Michigan State University
2011-2015 – Dean’s List, Michigan State University


1) Wu, S., Liu, F., Gai, Y., Carter, J., Edwards, H., Hüttemann, M., Wang, G., Li, C., Taub, J., Wang, Y., Ge, Y. Combining the Novel FLT3 and MERTK Dual Inhibitor MRX-2843 with Venetoclax Results in Promising Antileukemic Activity Against FLT3-ITD AML. BMC Cancer. Accepted 2024 Jan.
2) Su Y, Carter JL, Li X, Fukuda Y, Gray A, Lynch J, Edwards H, Ma J, Schreiner P, Polin L, Kushner J, Dzinic SH, Buck SA, Pruett-Miller SM, Hurrish KH, Robinson C, Qiao X, Liu S, Wu S, Wang G, Li J, Allen JE, Prabhu VV, Schimmer AD, Joshi D, Kalhor-Monfared S, Watson IDG, Marcellus R, Isaac MB, Al-Awar R, Taub JW, Lin H, Schuetz JD, Ge Y. The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer Research. 2024 Jan 24.
3) Hurrish KH, Su Y, Patel S, Ramage CL, Zhao J, Temby BR, Carter JL, Edwards H, Buck SA, Wiley SE, Hüttemann M, Polin L, Kushner J, Dzinic SH, White K, Bao X, Li J, Yang J, Boerner J, Hou Z, Al-Atrash G, Konoplev SN, Busquets J, Tiziani S, Matherly LH, Taub JW, Konopleva M, Ge Y, Baran N. Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro. Biochemical Pharmacology. 2023 Dec 10;220:115981.
4) Carter JL, Su Y, Qiao X, Zhao J, Wang G, Howard M, Edwards H, Bao X, Li J, Hüttemann M, Yang J, Taub JW, Ge Y. Acquired resistance to venetoclax plus azacitidine in acute myeloid leukemia: In vitro models and mechanisms. Biochemical Pharmacology. 2023 Oct;216:115759.
5) Al-Antary ET*, Gupte A*, Carter J.*, Kaafarani M, Howard M, Edwards H, Ge Y, Taub JW. Curing childhood cancer the "Natural" Way: Nature as the source of chemotherapy agents. Biochemical Pharmacology. 2023 Jul;213:115630. *co-first authors
6) Hurrish, KH., Qiao, X., Li, X., Su, Y., Carter, J., Ma., J., Kalpage, HA., Huttemann, M., Edwards, H., Wang, G., Kim, S., Dombkowski, A., Bao, X., Li, J., Taub, J., Ge, Y. Co-targeting of HDAC, PI3K, and Bcl-2 Results in Metabolic and Transcriptional Reprogramming and Decreased Mitochondrial Function in Acute Myeloid Leukemia. Biochemical Pharmacology. 2022 Sept 28.
7) Wu, S., Edwards, H., Wang, D., Liu, S., Qiao, X., Carter, J., Wang, Y., Taub, J., Wang, G., Ge, Y. Inhbition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-mutated Acute Myeloid Leukemia. Cells. 2022 Sept 3.
8) Carter JL, Hege K, Yang J, Kalpage HA, Su Y, Edwards H, Hüttemann M, Taub JW, Ge Y. Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy. Signal Transduction Target Therapy. 2020 Dec 18;5(1):288.
9) Carter JL, Hege K, Kalpage HA, Edwards H, Hüttemann M, Taub JW, Ge Y. Targeting mitochondrial respiration for the treatment of acute myeloid leukemia. Biochemical Pharmacology. 2020 Dec;182:114253.
10) Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y. Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation. Cancers (Basel). 2020 Aug 24;12(9):2400.
11) Read, GH., Miura, N., Carter, JL., Kines, KT., Yamamoto, K., Devasahayam, N., Cheng, JY., Camphausen, KA., Krishna, MC., Kesarwala, AH. Three-dimensional alginate hydrogels for radiobiological and metabolic studies of cancer cells. Colloids and Surfaces B: Biointerfaces. November 1, 2018.
12) Sporer, KRB, Carter, JL., Coussens, PM. The PBS-12SF Cell Line: Development of an Alternative Cell Line for Influenza Vaccine Production. Journal of Vaccines & Vaccination. November 1, 2016.
13) Carvajal-Yepes, M., Sporer, KRB., Carter, JL., Colvin, CJ., and Coussens, PM. Enhanced production of human influenza virus in PBS-12SF cells with a reduced interferon response. Human Vaccines and Immunotherapeutics. June 19, 2015.

Other Information

 • WSUSOM Student Senate (2018 – Present)
• WSUSOM Student Senate Executive President (2021 – 2022)
• Aseculapians Honor Society Member (2020 – Present)
• Admissions Committee Member (2019 – Present)
• American Physicians Scientists Association (2019 – 2020)
• Physicians for Social Responsibility (2018-2019)
• Participant in many efforts to improve medical education at WSUSOM!


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