School of Medicine

Wayne State University School of Medicine

Recent PhD Graduates

 

August 2012-December 2012 PhD Graduates

Mohammad Al Zubi
Major:
Pharmacology
Advisor: Emmanuel Ayorinde
Dissertation Title: Investigation and Improvement of Noise, Vibration and Harshness (Nvh) Properties.

 

Monica Bame
Major:
Biochemistry & Molecular Biology

Advisor:  William Brusilow
Dissertation Title:  Understanding the Gender-Specific Effects of MSO Treatment in ALS Mice: A Metabolic Characterization of the SOD1-G93A Mouse Model.

Sita Desmoulin
Major:
Cancer Biology
Advisor: Larry Matherly
Dissertation Title: The Human Proton-Coupled Folate Transporter: Biology and Therapeutic Applications to Cancer.

Prasanna Ekambaram
Major:
Cancer Biology
Advisor: Kenneth Honn
Dissertation Title: Role of Thromboxane Receptors-alpha in Prostate Cancer Progression.

David Fischer
Major:
Immunology & Microbiology
Advisor: Roy Sundick
Dissertation Title: Membrane-Bound Immunomodulators as Adjuvants in a Cell Culture-Based Avian Influenza Vaccine.

Xiaoyu Jiang
Major:
Anatomy & Cell Biology
Advisor: Linda Hazlett
Dissertation Title: VIP and Host Immunity.

Sangeeta Joshi
Major:
Pathology
Advisor: Kenneth Honn
Dissertation Title: A Novel Interaction Between 12-Lipoxygenase and 4 Integrin Plays a Role in Cancer Progression.

Suresh Kari
Major:
Immunology & Microbiology
Advisor: Yi-Chi Kong
Dissertation Title: Examining Autoimmune Sequelae During Cancer Immunotherapy in a Combined Autoimmune Thyroiditis and Tumor Mouse Model.

Hitchintan Kaur
Major:
Pharmacology
Advisor: Raymond Mattingly
Dissertation Title: Analysis of Gene Expression Alterations in Premalignant Progression from Normal Mammary Epithelium to Ductal Carcinoma in Situ by Multiple Orthogonal Tools.

John Lillvis
Major:
Molecular Biology & Genetics
Advisor: Wayne Lancaster and Helena Kuivaniemi
Dissertation Title: Towards an Understanding of the Etiology of Abdominal Aortic Aneurysms: Identification of Genes Implicated in AAA Risk and Development.

Dumrong Mairiang
Major:
Molecular Biology & Genetics
Advisor: Russell Finley
Dissertation Title: Characterizationof Intracellular Interactions Between Dengue Virus and Host Proteins.

Michael Price
Major:
Cancer Biology
Advisor: David Kessel
Dissertation Title: A Role for Reactive Oxygen Species in Photodynamic Therapy.

Jianbin Shen
Major:
Molecular Biology & Genetics
Advisor: Li Li
Dissertation Title: Identifying SM22 as a Key Player in Arterial Diseases.

Angela Sosin
Major:
Cancer Biology
Advisor: Ayad Al-Katib
Dissertation Title: HDM2 Small-Molecule Inhibitors for Therapeutic Intervention in B-Cell Lymphomas.

Daochun Sun
Major:
Molecular Biology & Genetics
Advisor: Michael Tainsky
Dissertation Title: Identification of Transcriptional Mechanisms Downstream of NF1 Gene Defeciency in Malignant Peripheral Nerve Sheath Tumors.

Carrie Tatar
Major:
Anatomy & Cell Biology
Advisor: Robert Skoff
Dissertation Title: Determinants of CNS Adult Neurogenesis Are Sex, Hormones, Mouse, Strain, Age, and Brain Region Specific.

 

May 2012 PhD Graduates

Daniel Barkmeier
Major: Molecular Biology & Genetics
Advisor: Jeffrey Loeb
Dissertation Title: The Interictal State in Epilepsy.

Song Chen
Major: Biochemistry & Molecular Biology
Advisor: David Evans
Dissertation Title: The Role of CAD, FLASH and FAM129B in Cancer Cell Survival and Apoptosis.

Brett Hanson
Major:
Immunology & Microbiology
Advisor: Melody Neely
Dissertation Title: Analysis of the Streptococcal CpsA Protein in DNA-Binding and Regulation of Capsule and Cell Wall maintenance.

Jill Jamison
Major:
Physiology
Advisor: Donald DeGracia
Dissertation Title: Mechanisms of Persistent Reanslation Arrest Following Global Brain Ischemia and Reperfusion.

Lesley Lawrenson
Major:
Molecular Biology & Genetics
Advisor: Hong-Qiang Heng
Dissertation Title: Tracking Profiles of Genomic Instability in Spontaneous Transformation and Tumorigenesis.

Yun-Hee Lee

Major:  Pathology
Advisor: Todd Leff
Dissertation Title: Cellular Plasticity in White Adipose Tissue: In Vivo Identification of Bipotent Adipocyte Progenitors in Adult White Adipose Tissue.

Victoria McIntosh
Major:
Physiology
Advisor: Robert Lasley
Dissertation Title: Sex Differences int he Cardiac β-Adrenergic Receptor Contractile Response.

Yong Wang
Major:
Biochemistry & Molecular Biology
Advisor: Ladislau Kovari
Dissertation Title: Drug Resistance Mechanisms and Drug Design Strategies for Human Immunodeficiency Virus and Hepatitis C Virus Proteases.

Lisi Yuan
Major:
Anatomy & Cell Biology
Advisor: Marc Basson
Dissertation Title: Molecular Mechanisms of Strain-Stimulated Intestinal Epithelial Cell Differentiation and Migration.
 

Fall 2011 PhD Graduates

Kadija Abounit
Major:
Pharmacology
Advisor: Roy McCauley
Dissertation Title: The Process of Autophagy in an In Vitro Model of Myocardial Ischemia-Reperfusion Injury.

Jonathan Allen
Major:
Immunology & Microbiology
Advisor: Melody Neely
Dissertation Title: Pleiotropic Regulatory Function of the LysR Family Transcriptional Regulator Cpsy During Streptococcus iniae Systemic Infection.

Bavneet Benipal
Major:
Pharmacology
Advisor: Lawrence Lash
Dissertation Title: Compensatory Renal Hypertrophy, Mitochondria and Redox Status.

Jiaqi Fu
Major:
Molecular & Cellular Toxicology
Advisor: Melissa Runge-Morris
Dissertation Title: Estrogen Sulfotransferase (SULT1E1) Expression and Function

Yuefei Huang
Major:
Biochemistry & Molecular Biology
Advisor: Jianjun Wang
Dissertation Title:  A Novel in Vivo Protein Refolding Technique.

Amruta Jambekar
Major:
Biochemistry & Molecular Biology
Advisor:  William Brusilow
Dissertation Title: Use of Methionine Sulfoximine to Dissect the Role of Glutamine Synthetase and Glutamine in Progression of Acute Liver Failure.

Philip Jessmon
Major:
Anatomy & Cell Biology
Advisor: David Armant
Dissertation Title: Human Trophoblast Survival and Invasion in the Developing Placenta: Autocrine Regulation by HBEGF.

Miriam Kleinman
Major:
Molecular & Cellular Toxicology
Advisor: John Reiners Jr.
Dissertation Title: Cationic Amphiphilic Drug-Induced Autophagosome Sequestration Within Vimentin Itermediate Filament Networks Results in Prolonged Autophagosome Half-Life.

Monique Lewis
Major:
Physiology
Advisor: Donald DeGracia
Dissertation Title: Mechanisms of Translation Arrest Following Focal Ischemia and Reperfusion.

Zhenzhong Ma
Major:
Molecular Biology & Genetics
Advisor: Jeffrey Loeb
Dissertation Title: Axoglial Communication Mediated by Soluble Neuregulin-1 and BDNF.

Main Maitah
Major:
Pathology
Advisor: Fazlul Sarkar
Dissertation Title: Hedgehog Signaling: A Potential Therapeutic Target for Non-Small Cell Lung Cancer.

Dhiman Maitra
Major:
Physiology 
Advisor: Husam Abu-soud 
Dissertation Title:
Destruction of Biological Tetrapyrrole Macrocycles by Hypochlorous Acid and Its Scavenging by Lycopene.

Victoria Murray
Major:
Biochemistry & Molecular Biology
Advisor: Jianjun Wang
Dissertation Title: Development of an In-cell Forster Resonance Energy Transfer Technique to Study Protein Structure Inside Living Cells.

Bernadette Victor
Major:
Cancer Biology
Advisor: Bonnie Sloane

Jennell White-Jackson
Major:
Physiology
Advisor: Ghassan Saed
Dissertation Title: A Potential Role for Innate Immunity in the Pathogenesis of Post-Operative Adhesions.

Leah Zhang
Major:
Physiology
Advisor: Bhanu Jena
Dissertation Title: Molecular Mechanisms of Snare Assembly and Expulsion of Intravesicular Contents in Cell Secretion.

Sichang Zhou
Major:
Physiology
Advisor: Daniel Rappolee

 

 

Fall 2010-August 2011 PhD Graduates

Basel Abuaita
Major:
Immunology & Microbiology
Advisor: Jeffrey Withey
Dissertation Title: Post-Transcriptional Regulation of Vibrio Cholerae Virulence Activator ToxT.

Andrea Baillo
Major:
Cancer Biology
Advisor: Stephen Eithier
Dissertation Title: Amphiregulin (AREG) and Epidermal Growth Factor (EGF): Disparate in EGFR Signaling and Trafficking.

Matthew Coutsos
Major:
Physiology
Advisor: Donal O'Leary
Dissertation Title: Muscle Metaboreflex Control of Coronary Blood Flow and Ventricular Contractility During Dynamic Exerciese in Normal and Heart Failure Conditions.

Heather Gibson
Major:
Immunology & Microbiology
Advisor: Wei-Zen Wei and Henry Wong
Dissertation Title: CTLA-4 Transcriptional Activation: Regulation of Induced Expression.

Jeremy Laukka
Major:
Molecular Biology & Genetics
Advisor: John Kamholz
Dissertation Title: Application of Magnetic Resonance Imaging to Understanding the Pathogenesis of the X-linked Leukodystrophy Pelizaeus-Merzbacher Disease.

Zhigang Liu
Major:
Biochemistry & Molecular Biology
Advisor: Ladislau Kovari
Dissertation Title: Crystallographic, Molecular Dynamics, and Enzymatic Studies of Multi-Drug Resistant HIV-1 Protease and Impkications for Structure Based Drug Design.

Heather McClung
Major: Pharmacology
Advisor: Sandra Rempel
Dissertation Title: The Role of SPARC Acidic Domain and EGF-like Module in Glioma Migration, Invasion, and Signaling.

Timothy McFarland
Major:
Physiology
Advisor: Steven Cala
Dissertation Title: Cardiac Calsequestrin Phosphorylation and Trafficking in the Mamalian Cardiomyocyte.

 

Phanramphoei Namprachan-Frantz
Major: Immunology & Microbiology
Advisor: Melody Neely
Dissertation Title: Identification of the Role of the Sal Locus in Streptococcus Pyogenes Virulence During Host-Pathogen Interactions.

Samar Nasser
Major:
Physiology

Advisor: John Flack
Dissertation Title: Effect of Dimethylarginine Dimethylaminohydrolase in the Development of Salt Sensitivity.

Irene Papanayotou
Major:
Pharmacology
Advisor: Nicholas Davis
Dissertation Title: Palmitoylation and the Yeast Casein Kinase, Yck2.

Swati Rawat
Major:
Biochemistry & Molecular Biology
Advisor:
Timothy Stemmler
Dissertation Title:
Molecular Details of the Mitochondrial Fe-S Cluster Assembly Pathway.

Anna Valina-Toth
Major:
Physiology
Advisor:
John Flack
Dissertation Title: Vitamin D and Parathyroid Hormone Relationships with Obesity, Nitric Oxide Metabolites, Oxidative Stress, Blood Pressure, Vascular Function and Salt Sensitivity in African Americans.

Alison Van Dyke
Major:
Cancer Biology
Advisor: Ann Schwartz
Dissertation Title: Inflammation in Non-Small Cell Lung Cancer: Associations with Risk and Survival in Women.

 

May 2009-August 2010 PhD Graduates

Adamson, Justus
Major: Medical Physics
Advisor: Qiuwen Wu/Jacob Burmeister
Dissertation Title: Prostate Intrafraction Motion Assessed by Simultaneous kV Flurorscopy at MV Delivery.

Conley-LaComb, M. Katie
Major: Cancer Biology
Advisor: H-R. C. Kim
Dissertation Title: Matriptase/PDGF D/---PDGFR Signaling Axis in Human Prostate Cancer: The Role of PTEN in the Regulation of PDGF D Expression.

Cook, Jeremy
Major: Biochemistry & Molecular Biology
Advisor: Timothy Stemmler
Dissertation Title: Frataxin, the Mitochondrial Iron Chaperone for Fe-S Cluster Bioassembly
.

Francis, Todd
Major: Physiology
Advisor: James Rillema, Ph.D. and Saroj Mathupala, Ph.D.
Dissertation Title: Metabolic Targeting of Malignant Glioma: Modulation of Glycolytic Flux by Erythropoietic Factors.

Gayer, Christopher
Major: Anatomy & Cell Biology
Advisors: Anatomy & Cell Biology
Dissertation Title: The Role of PI3K, AKT and ERK in Strain-Induced Cell Migration and Proliferation.

Gibson, Tiffini
Major: Physiology with a Reproductive Science Concentration
Advisor: Carol Brenner, Ph.D.
Dissertation Title: The Impact of the Mitochondrial DNA Genome on Skeletal Muscle and Preimplantation Development in the Rhesus Macaque.

Jiang, Xuan
Major
: Biochemistry & Molecular Biology
Advisor: Barry Rosen
Dissertation Title: Properties and Mechanism of Trivalent Arsenicals Transport by Mammalian Glucose Permease GLUT1.

Kallakuri, Srinivasu
Major: Anatomy & Cell Biology
Advisor: Jose Rafols
Dissertation Title: The Endothelin Receptor and Axonal Degeneration in a Model of Diffuse Brain Injury.

Kfoury, Najla
Major:
Molecular Biology & Genetics
Advisor: Gregory Kapatos
Dissertation Title: Differential target gene recruitment and cellular distribution of CCAAT/Enhancer Binding Proteins alpha, beta and delta in the rodent brain.

Kotsis, Damian
Major: Biochemistry & Molecular Biology
Advisor: David Evans
Dissertation Title: Regulation of De Novo Pyrimidine Biosynthesis by CAD and CTP Synthetase.

Muralidharan, Sandhya
Major:
Biochemistry & Molecular Biology
Advisors: Bharati Mitra
Dissertation Title: Investigating the Metal Binding Sites in ZNTA, a Zinc Transporting ATPase.

Sanki-Tarbichi, Abdul
Major: Physiology
Advisor: Safwan Badr, M.D.
Dissertation Title: Effect of ventilatory motor Output on Upper Airway Mechanics during Sleep.

Wu, Minhao
Major: Anatomy & Cell Biology
Advisor: Linda Hazlett
Dissertation Title: Defensins in Ocular Immunity.

Yang, Jianbo
Major: Biochemistry & Molecular Biology
Advisor: Barry Rosen
Dissertation Title: Characterization of ArsD: an Arsenic Chaperone for the ArsABAs(III)-translocating ATPase.

Yedidi, Ravikiran
Major: Biochemistry & Molecular Biology
Advisor: Ladislau Kovari
Dissertation Title: Structure Based Design of Potent Inhibitors Against Multidrug-resistant HIV-1 Protease Variants.

Zhang, Lin
Major: Pathology
Advisor: Todd Leff
Dissertation Title: A direct link between cellular metabolism and gene expression: AMP-activated protein kinase as a transcriptional co-repressor.

Zhang, Yi
Major: Anatomy & Cell Biology
Advisor: Zhuo-Hua Pan
Dissertation Title: The Expression, Physiology, Neurotoxicity and Modulation of Microbial-Type Rhodopsins in Retinal Neurons.


Zhou, Zimei
Major: Anatomy & Cell Biology
Advisor: Linda Hazlett
Dissertation Title: Apoptosis in Ocular Inflammation.

 

 

August 2008-May 2009 PhD Graduates

 

Arnold, Alan
Major: Cancer Biology
Advisor: Ramzi Mohammad
Dissertation Title: Small-Molecule Inhibitors targeting survival pathways in B-cell Lymphoma.

Boyer, Alaina
Major: Cancer Biology
Advisor: 
Stephen Ethier
Dissertation Title: Effects of HER-2 Over Expression in Human Mammary Epithelial Cells: Evidence of Altered HER-2 Signaling and Crosstalk Between Insulin and EGF Signaling.

Chirco, Rosemarie
Major: Cancer Biology
Advisor: H-R. C. Kim
Dissertation Title: The Novel Functions of TIMP-1: Regulation of Apoptosis and Epithelial-Mesenchymal Transition in Breast Epithelial Cells.

Chunta, John
Major: Anatomy & Cell Biology
Advisor: Rodney Braun
Dissertation Title: Radiosensitizing Hypoxic Tumors Through Metabolic Inhibition.

Craig, David
Major: 
Cancer Biology
Advisor: Marc Basson

Dissertation Title:  Mechanical Signaling Mechanisms Underlying Pressure-Stimulated Tumor Cell Adhesion.

Daffu, Gurdip
Major:
Molecular Biology & Genetics
Advisor: John Kamholz

Dissertation Title: An Investigation of the role of the Proteolipid Protein Specific Domain in Central Nervous System Myelin.

Deng, Yijun
Major:
Cancer Biolgoy
Advisor: Larry Matherly
Dissertation Title: Structure and Function of Folate Transporters: Role in Development of Anticancer Drugs.

Dodge, Charles
Major:
Medical Physics
Advisor: Michael Flynn and Jay Burmeister
Dissertation Title: A Rapid Method for the Simulation of Filtered X-Ray Spectra in Diagnostic Imaging Systems.

Dupont, Catherine
Major:
Physiology

Advisor: Carol Brenner
Dissertation Title: Incidence and Mechanisms of Chromosomal Anomalies during Early Development of Rhesus Macaques.

Fusinski, Keith
Major:
Immunology & Microbiology
Advisor: Thomas Holland
Dissertation Title: Adenovirus 36 E4orf1 Gene Induces Differentiation of 3T3-L1 Cells.

Huang, Yonglu
Major:
Anatomy & Cell Biology
Advisor: Harry G. Goshgarian
Dissertation Title: Changes in the Crossed Phrenic Pathway and Crossed Phrenic Activity During Postnatal Development.

Jedeszko, Christopher
Major: Pharmacology
Advisor: Bonnie Sloane
Dissertation Title: 3D Organotypic Cultures of Ductal Carcinoma In Situ Model the effects of Stroma on Brease Cancer Progression.

 

Kent, Tiffany
Major: Physiology
Advisors: Raymond Iezzi and James Rillema
Dissertation Title: Drug Delivery Methods & Pharmacological Approaches for Treatment of Retinal Degenerative Diseases and its Applicability for Improving Visual Function as Mediated by Artificial Approaches.

Kheradmand, Taba
Major:
Immunology & Microbiology
Advisor: Robert Swanborg
Dissertation Title: Natural Killer Cells and their Role in the Regulation of T cell Proliferation.

Kizy, Anne
Major:
Immunology & Microbiology
Advisor: Melody Neely
Dissertation Title: A genetic exploration reveals novel Streptococcus pyogenes virulence factors important for in vivo survival and biofilm.

Kona, Fatima
Major:
Biochemistry & Molecular Biology
Advisor: Domenico Gatti
Dissertation Title: Structure-Function Studies of Aquafax aeolicus 3-Deoxy-D-Manno Octulosonate 8-Phosphate (KD08P) Synthase.


Kondapalli, Kalyan
Major:
Biochemistry & Molecular Biology
Advisor: Tim Stemmler
Dissertation Title: Structure-Function Studies of Frataxin: An Iron Chaperone in the Mitochondrial Fe-S Cluster and Heme Biosynthetic Pathways.

Masko, Elizabeth
Major: Cancer Biology
Advisor: David Evans
Dissertation Title: Intracellular regulation of the multifunctional protein CAD in breast cancer.

Massey, Katherine
Major:
Physiology
Advisor: Douglas Yingst
Dissertation Title: Role of Phosphorylation of the Alpha-subunit in Mechanisms Regulating the Activity of the Rate Kidney Na, K-ATPase by Angiotensin II.

Milacic, Vesna
Major: Cancer Biology
Advisor: Q. Ping Dou

Dissertation Title: The ubiquitin-proteasome pathway as a molecular target for potential anticancer agents.

Nautiyal, Jyoti
Major:
Cancer Biology
Advisor: Adhip Majumdar
Dissertation Title: Targeting Multiple Signaling in Breast and Colon Cancers.

Sabbota, Aaron
Major: Cancer Biology

Advisor: Michael Cher
Dissertation Title:
Prostate Cancer Progression and Tumor-Induced Osteolysis: Implications of a Tumor-Associated MT1-MMP/RANKL/RANK Singaling Axis.

Saeed Tehrani, Omid
Major: Cancer Biology
Advisor: Anthony Shields
Dissertation Title: Studying kinetics and cellular metabolism of pyrimidine based analogs as pet imaging agents.

Satkunendrarajah, Kajana
Major: Anatomy & Cell Biology
Advisor: Harry Goshgarian
Dissertation Title: 3', 5'-Cyclic Monophosphate-Mediated Respiratory Recovery Following High Cervical Spinal Cord Hemisection.

Sivashanmugam, Arun
Major:
Biochemistry & Molecular Biology
Advisor: Jianjun Wang
Dissertation Title: Structural Studies and Functional CHaracterization of Exchangeable Apolipoproteins in Lipoprotein Formation and Transport.


Smyczynski, Mark
Major: Medical Physics
Advisor: Michael King and Otto Muzik
Dissertation Title: An Investigation of the Impact and Correction of Respiratory Motion on the Detection of Small Lung Lesions in SPECT Imaging.

Wojtkowiak, Jonathan
Major: Pharmacology
Advisor: Raymond Mattingly
Dissertation Title: The Induction of Apoptosis and Autophagy in Malignant Peripheral Nerve Sheath Tumor Cells by a Combination of Prenylation Inhibitors.

Yedidi, Ravi Kiran
Major: Biochemistry & Molecular Biology
Advisor: Ladislau Kovari
Dissertation Title: Structure Based Design of Potent Inhibitors Against Multidrug-Resistant HIV-1 Protease Variants.


 

 August 2007-May 2008 PhD Graduates

Beaumont, Thomas
Major
: Molecular Biology & Genetics
Advisor: Jeffrey Loeb
Dissertation Title: Defining the Human Epileptic Transcriptome.

Brown, Nicholas
Major:  
Immunology & Microbiology
Advisor: Yi-Chi Kong
Dissertation Title: Examination of the Roles of MHC Classll Molecules and Regulatory T Cells in Experimental Autoimune Thyroiditis.

Campbell, Janice
Major:
Medical Physics
Advisor: Jay Burmeister
Dissertation Title: Development of Dose Response to Y-90 Microsphere Treatment of Metastatic Liver Cancer by Quantitative Analysis of Spect and Pet Images.

Chandran, Nitya
Major:
Cellular & Clinical Neurobiology
Advisor: Gregory Kapatos
Dissertation Title: Characterization of The Rat GTP Cyclohydrolase I (GCHI) GC-Box and Its Cognate Binding Proteins.

Cho, Jinah
Major:
Physiology
Advisor: Rafael Fridman
Dissertation Title: Biochemical and Biological Studies on the Regulation of MT1-MMP (MMP-14) at the Tumor Cell Surface.

Dzinic, Sijana
Major:
Physiology
Advisor: Jeffrey Ram
Dissertation Title: Chemotaxis and Mechanisms Mediating Escherichia Coli-Host Specificity.

Elliott, Althea
Major:
Molecular & Cellular Toxicology
Advisor: John Reiners
Dissertation Title: Regulation of the Aryl Hydrocarbon Receptor by Ubiquitin Conjugating Enzyme Inhibitor P-Anilinoaniline.

Glide, Carrie
Major:
Medical Physics
Advisor: Neb Duric
Dissertation Title: A Novel Approach to Evaluating Breast Density Using Ultrasound Tomography.

Hurst, Newton
Major: Cancer Biology
Advisor: Hygong-Reh Kim
Dissertation Title: Molecular Mechanisms of Platelet-Derived Growth Factor-CC (PDGF-CC) Activation by Serine Proteases: Implications For Breast Cancer Progression.

Kayali, Foaz
Major:
Physiology
Advisor: Donald DeGracia
Dissertation Title: The Role of Stress Granules in Persistent Translation Arrest In The Post Ischemic Hippocampus.

Krueger, Sarah
Major:
Cancer Biology
Advisor: Michael Joiner
Dissertation Title: Regulation of The G2 Cell-Cycle Checkpoints In Response to Low-Dose Ionizing Radiation.

Landis-Powowar, Kristin
Major:
Cancer Biology
Advisor: Q. Ping Dou
Dissertation Title: Molecular Studies on Stability, Biotransformation, and Cellular Targets of Dietary Polyphenois: Implications in Human Cancer Prevention and Treatment.

Leicht, Deborah
Major: Pathology
Advisor: Guri Tzivion
Dissertation Title: RAF-1 Regulation By Its Downstream Effectors, MEK and ERK.

Lenk, Guy
Major: Molecular Biology & Genetics
Advisor: Helena Kuivaniemi
Dissertation Title: Refinement of the Genetic Susceptibility Loci for Abdominal Aortic Aneurysms.

Lomonaco, Stephanie
Major: Molecular & Cellular Toxicology
Advisor: Gan Wang
Dissertation Title: The Role of Nucleotide Excision Repair in DNA Damage Mediated Apoptosis and Cell Cycle Regulation.

Lowe, Beth
Major: Immunology & Microbiology
Advisor: Melody Neely
Dissertation Title: Analysis of Systematic Dissemination of the Zoonotic Pathogen Streptococcus Iniae and the Importance of Capsule.

Milstein, Michelle
Major:
Physiology
Advisor: Steven Cala
Dissertation Title: Triadin Glycosylation and Calcium Release Complexes in Heart.

Radkevich, Olga
Major:
Cancer Biology
Advisor: Wei-Zen Wei
Dissertation Title: Her-2 DNA Vaccination and Intratumoral Immune Modulation.

Ritchie, Raquel
Major:
Molecular Biology & Genetics
Advisor: Li Li
Dissertation Title: Understanding the Transcriptional Regulatory Network of Smooth Muscle Genes in Response to TGF-Beta Signaling.

Sun, Qing
Major:
Pathology
Advisor: Rafael Fridman
Dissertation Title: Biochemical and Biological Characterization of Membrane Type 6-Matrix Metalloproteinase.

Swamydas, Muthulekha
Major: Anatomy & Cell Biology
Advisor: Robert Skoff
Dissertation Title: Role of Hormones in the Sexual Dimorphism of Oligodendrocytes.

Whittington, Paula
Major: Immunology & Microbiology
Advisor: Wei-zen Wei
Dissertation Title: Her-2 Vaccines: Mechanism of Action and Clinical Implications.

Yang, Hung-Chi
Major:
Biochemistry & Molecular Biology
Advisor: Barry Rosen
Dissertation Title: Functional and Structural Studies of a Novel Arsenic Detoxification Pathway in the Legume Symbiont Sinorhizobium Meliloti.

Yin, Jia
Major:
Anatomy & Cell Biology
Advisor: Fu-Shin Yu
Dissertation Title: Molecular Regulation of Corneal Epithelial Would Healing.

Young, Chen-Ning
Major:
Physiolgoy
Advisors: L. Boyd Savoy and Stanley Terlecky
Dissertation Title: Role of Reactive Oxygen Species in the - Activated Human Primary Keratinocytes: Implication for Psoriasis.

Yu, Jiayi
Major: Immunology & Microbiology
Advisor:  Michael Shaw
Dissertation Title: Interleukin 13 D E2-A Novel Splice Variant of Interleukin-13 with inflammatory Function.


 

August 2006 - May 2007 PhD Graduates

Abu-Hamdah, Rania
Major:  Physiology
Advisor:  Jena Bhanu 
Dissertation Title: Regulation of the Water Channel Aquaporin 1and Aquaporin 6: Isolation and Reconstitution of the Regulatory Complex.

Dilworth, Joshua
Major:  Pharmacology
Advisor:  Raymond Mattingly 
Dissertation Title: The EGFR:RAS Axis In Malignant Peripheral Nerve Sheath Tumor Cells

Fridman, Aviva R.
Major:  Cancer Biology
Advisor:  Michael Tainsky 
Dissertation Title: Gene Expression Pathways Altered In Cellular Immortalization

Glaros, Selina
Major:  Cancer Biology
Advisor:  Kaladher Reddy 
Dissertation Title: The Role Of MAPK,AKT, and ER alpha in Tamoxifen Resistant Breast Cancer

Hu, Caiping
Major:  Anatomy and Cell Biology
Advisor:  Zhuo-Hua Pan 
Dissertation Title: Voltage Gated Calcium Channels in retinal bipolar cells

Koepke, Jay
Major:  Physiology
Advisor:  Stanley Terlecky 
Dissertation Title: Peroxisome Senescene And The Role OF Catalase Import In Cellular Aging

Krishnamoorthy, Sriram
Major:  Cancer Biology
Advisor:  Kenneth Honn 
Dissertation Title: 12-Lipoxygenase and Prostate Cancer Angiogenesis in the Normoxic and Hypoxic Microenvironment

Krolewski, David
Major:  Anatomy and Cell Biology
Advisor:  Paul Walker 
Dissertation Title: Dopamine D1 and D2 Receptor-Mediated Immediate-Early Gene Expression in the Striatum and Frontal Cortex and Its Relationship to Motor Behaviors in the Rat.

Lin, Yung-Feng
Major:  Biochemistry
Advisor:  Barry Rosen 
Dissertation Title: An Arsenic metallochaperone for an arsenic detoxification pump

Lockett, Jaron
Major:  Pathology
Advisor:  Shijie Sheng 
Dissertation Title: Maspin As A Regulator Of Extracellular Matrix Proteolysis

Phelps, Hilary
Major:  Immunology and Microbiology
Advisor:  Melody Neely 
Dissertation Title: Characterization of streptococcus pyogenes factors required for host-pathogen interactions

Sanderson, Thomas
Major:  Physiology
Advisor:  Gary Krause 
Dissertation Title: Insulin-Mediated Suppression Of Cytochrome C Release From Mitochondria After Transient Brain Ischemia

Sawarynski, Kara
Major:  Cancer Biology
Advisor:  George Brush 
Dissertation Title: Characterization Of A Cyclin-Dependent Kinase Inhibitor During Meiosis IN Yeast

Schaubert, Keri
Major:  Immunology and Microbiology
Advisor:  June Kan-Mitchell 
Dissertation Title: Characterization And exploitation Of the Human T Cell Repertoire To A Potentially Protective HIV-1 Epitope In GAG p24

Speshock, Janice
Major:  Immunology and Microbiology
Advisor:  Christopher Roberts 
Dissertation Title: Fatal Bacteremia Occurs In Mice Co-Infected with Filamentous Influenza A Virus And Serotype 3 Streptococcus Pneumoniae

Szliter, Elizabeth
Major:  Anatomy & Cell Biology
Advisor:  Linda Hazlett 
Dissertation Title: Vasoactive Intestinal Peptide:Immunoregulatory Role In Occular Inflammation

Wang, Zhiwei
Major:  Pathology
Advisor:  Fazlul Sarkar 
Dissertation Title: Notch signaling:A pothentical therapeutic target for pancreatic cancer

Wood, Christopher
Major:  Pharmacology
Advisor:  Stanley Terlecky 
Dissertation Title: Cellular characterization of human hypocatalasemia and the role of PEX 14 P phosphorylation in peroxisome biogenesis

Zhong, Wenjing
Major:  Anatomy and Cell Biology
Advisor:  Dan Rappolee 
Dissertation Title: Stress and Elevated MAPK8,9 Phospho Mediate Decreased Growth And Induce Differentiation Of Trophoblast Stem Cell During Implantation

Zhou, Yao
Major:  Biochemistry
Advisor:  Barry Rosen 
Dissertation Title: Biochemical And Functional Studies On The Eukaryotic Arsenate/Antimonate Reductases

  

 

May 2006 PhD Graduates

Abdelmegeed, Mohamed
Major:   Anatomy and Cell Biology
Advisor:   Raymond Novak  
Dissertation Title : The Activation of Signaling Pathways and the Regulation of Heme-Oxygenase 1 and Cytochrome P4502E1 by Ketone Bodies in Primary Cultured Rat Hepatocytes

Alilain, Warren
Major:   Cellular and Clinical Neurobiology
Advisor:   Harry Goshgarian  
Dissertation Title : NMDA and AMPA Receptor Subunit Plasticity in the Phrenic Motor Nucleus Following Chronice Upper Cervical Level Spinal Cord Injury in the Rat

Alyousef, Khalid
Major:   Medical Physics
Advisor:   Mark Yudelev  
Dissertation Title : A Novel Approach to Mixed Field Dosimetry Utilizing a Prototype Silicon Based P-1-N Diodes

Imad, Mays
Major:   Cellular and Clinical Neurobiology
Advisor:   Thomas Fischer  
Dissertation Title : 5-HT2A Receptor Activation Excites a Subpopulation of Pyramidal Cells in Deep Layer V of the Rat Prefrontal Cortex

Li, Gang
Major:   Pathology
Advisor:   Todd Leff  
Dissertation Title : Molecular Anaylsis of PPARy Mutations Associated with Diabetes and Lipodystrophy

Payton, Scott
Major:   Pharmacology
Advisor:   Larry Matherly  
Dissertation Title : Transcriptional and Post-Transcriptional Regualtion of the Human Reduced Folate Carrier Gene

Roshy, Stefanie
Major:   Cancer Biology
Advisor:   Bonnie Sloane  
Dissertation Title : The Role of Protesases During Development and Malignant Progression of the Mammary Acinar Structure In Vitro

Shi, Jinghua
Major:   Pathology
Advisor:   Lucia Schuger  
Dissertation Title: P311 Induces Myofibroblast Amebiod-Like Migration Through Rala Activation

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Fall 2005 PhD Graduates

Albertson, Dawn
Major:   Cellular and Clinical Neurobiology
Advisor:   Michael Bannon  
Dissertation Title : Gene Expression Profiles of Drug Abuse: An Analysis of Transcriptome Alterations in the Nucleus Accumbens of Human Cocaine and Heroin Abusers

Colen, Chaim
Major:   Physiology
Advisor:   Andrew Sloan  
Dissertation Title : Gene Therapy and Radiation of Malignant Glioma by Targeting Glioma Specific Lactate Transporter

Hill-Pryor, Crystal  
Major:   Physiology
Advisor:   Joseph Dunbar  
Dissertation Title : The Leptin-Proopiomelanocortin (POMC) Regulation of Cardiovascular Dynamics in Rats

Parks, Quinn
Major:   Immunology and Microbiology
Advisor:   Jeffrey Hobden  
Dissertation Title : Determinants of Pseudononas Aeruginosa Ocular Virulence

Roberts, George
Major:   Immunology and Microbiology
Advisor:   Alan Hudson  
Dissertation Title: In Yeast, the RSF1 Gene Product Functions in the Transition From Fermentative to Glycerol-Based Respiratory Growth

Sigoillot, Frederic
Major:   Biochemistry
Advisor:   Hedeel Guy-Evans  
Dissertation Title : Phosphorylation of the Multifunctional Protein CAD by MAP Kinase, PKA and PKC Cascades Leads to the Cellular Control of De Novo Pyrimidine Biosynthesis and is Associated with Differential Localizations of CAD

Sin, Mihaela
Major:   Cellular and Clinical Neurology
Advisor:   Michael Bannon  
Dissertation Title : Development of Experimental Models to Study the Expression of the Preprotachykinin-A Gene in the Striatum

Steele III, John
Major:   Physiology
Advisor:   J Pat McAlliester  
Dissertation Title: Patterns of Neuronal Degeneration in a New Muring Model of Diffuse Closed Head Injury (CHI)

Sun, Beimeng
Major:   Pharmacology
Advisor:   Nicholas Davis  
Dissertation Title : The Yeast Casein Kinase YCK3P is Pamitoylated, then Sorted to the Vacuolar Membrane with AP-3 Dependent Recognition of a YXX Adaptin Sorting Signal

Taylor, Jennifer
Major:   Cellular and Clinical Neurology
Advisor:   Paul Walker  
Dissertation Title: The Contribution of Serotonin 2A Receptors to Excessive Motor Behaviors Related to Dopamine Receptor Supersensitivity in a Rat Model of Parkinson's Disease

Yang, Yufang
Major:   Immunology and Microbiology
Advisor:   Roy Sundick  
Dissertation Title : A Novel Method to Produce Avian Influenza Vaccine Bearing Membrane-Bound Chil-2


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May 2005 PhD Graduates

Kim, Jong-Kyung
Major: Physiology
Advisor: Donal O'Leary
Dissertation Title: Interaction Between the Arterial Baroreflex and Muscle Metaboreflex


Lighvani, Shahrzad
Major: Anatomy and Cell Biology
Advisor: Linda Hazlett
Dissertation Title: The Role of Neuropeptides in Pseudomonas Aeruginosa Cornell Infection


Miller, Janet
Major:
Physiology
Advisor: J.P. McAllister
Dissertation Title: Gene Expression in Congenital Hydrocephalus and the Subsequent Effects of Gliosis


Miller, Jesse
Major: Immunology and Microbiology
Advisor: Melody Neely
Dissertation Title: Large Scale Screen Highlights the importance of Capsule for the Systemic Zoonotic Pathogen, Strptococcus iniae


Montie, Heather
Major: Physiology
Advisor: Donald DeGracia
Dissertation Title: The Unfolded Protein Response: Differentiation, Nitric Oxide and Ischemic Injury


Osenkowski, Pamela
Major:
Cancer Biology
Advisor: Rafael Fridman
Dissertation Title: Regulation of Membrane Type 1 - Matrix Metalloproteinase (MT1-MMP) on the Cell Surface


Sala-Mercado, Javier
Major:
Physiology
Advisor: Donal O'Leary
Dissertation Title: Muscle Metaboreflex Control of Ventricular Contractility During Dynamic Exercise in Normal and Heart Failure Conditions


Trivedi, Prachi
Major:
Immunology and Microbiology
Advisor: Robert Swanborg
Dissertation Title: Mechanism of Regulation of T Cell Responses by Natural Killer (NK+ CD3-) Cells

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Fall 2004 PhD Graduates

Anderson, Jamie
Major: Physiology
Advisor: Barry Franklin
Dissertation Title: Comparison of Thrombotic and Fibrinolytic Responses to Submaximal and Maximal Arm Versus Leg Exercise in Patients with Coronary Artery Disease

Blouse, Grant
Major: Pharmacology
Advisor: Joseph Shore
Dissertation Title: Protien Engineering of Plasminogen Activator Inhibitor-1 Provides New Insights into the Inhibition Mechanism of Serpins

Britton, Mark
Major: Physiology
Advisor: Joseph Dunbar
Dissertation Title: The Effects of Middle Cerebral Artery Occlusoions on CNS Apoptotic Events in Normal and Diabetic Rats

Cao, Wei
Major: Pharmacology
Advisor: Ray Matherly
Dissertation Title: Characterization of Membrane Topology and a Substrate-Binding Domain of the Human Reduced Folate Carrier

Castelli, Michelle
Major: Cancer Biology
Advisor: David Kessel
Dissertation Title: Mechanisms by Which the Bile Acid UDCA Enhances the Efficacy of BCL-2 Targeting Photodynamic Therapy

Chandana, Sreenivasa
Major: Pharmacology
Advisor: Diane Chugani
Dissertation Title: Functional Neuoimaging of Autism Using Positron Emission Tomography

Conant, Stephaine
Major: Immunology and Microbiology
Advisor: Robert Swanborg
Dissertation Title: Amino Acid Recognition of Encephalitogenic Myelin Peptides and the Participation of Innate Immunity in Expiramental Autoimmune Encephalomyelitis Induction

Delazerda, Alberto
Major: Medical Physics
Advisor: Colin Orton
Dissertation Title: Inverse Planning For Low-Dose-Rate Prostate Brachytherapy By Simulated Annealing Under Fuzzy Expert Controll

Feroze-Merzoug, Farhana
Major: Cancer Biology
Advisor: Fazlul Sarkar Yong Chen
Dissertation Title: Androgen Regulation of the Vascular Endothelial Growth Factor (VEGF) and its Receptor in Prostate Cancer

Franklin, Michael
Major: Physiology
Advisor: Dixon Woodbury
Dissertation Title: Calculation, Comparison and Modeling of SingleChannel Proton Flux Across Reconstituted Wildtype and Lutnat Fo of the F1F0 Atpase From Eschichia Coli

Greene, Sonya
Major: Immunology and Microbiology
Advisor: Nancy Freitag
Dissertation Title: Characterization of PRFA-Regulated Virulence Gene Expression in Listeeria Monocytogenes

Hart, Dawn
Major: Cancer Biology
Advisor: George Brush
Dissertation Title: Meiosis-Specific Phosphorylation of Replication Protein A: A Mechanistic and Functional Analysis

Henry, Scott
Major: Molecular Biology and Genetics
Advisor: Scott Dulchavsky
Dissertation Title: Biolistic Augmentation of Wound Healing in Diabetic and Steroid Treated Rats

Hinton, Ayana
Major: Biochemistry and Molecular Biology
Advisor: Sharon Ackerman
Dissertation Title: Probing the Mechanisms of ATP11P and ATP12P Through Biochemical and Molecular Biological Studies."

Jiang, Yong
Major: Biochemistry and Mocular Biology
Advisor: Barry Rosen
Dissertation Title: Mechanisms of Insulator-Like Element and the Nucleutide Binding Domains of a Resistance Pump

Kreipke, Christian W.
Major: Cellular and Clinical Neurobiology
Advisor: Paul Walker
Dissertation Title: NMDA and D1 Receptor Mechanisms of Movement Control: Differential Regulatory Mechanisms in the Intact and Dopamine Depleted Striatum

Li, Qunfang
Major: Molecular Biology and Genetics
Advisor: Jeffrey Loeb
Dissertation Title: Neuregulin-Extracellular Matrix Interactions in Synaptic Development and Cancer

Liu, Ming
Major: Biochemistry and Molecular Biology
Advisor: Richard Needleman
Dissertation Title: Targets of Phenylbutyrate - A Differentiating Agent - In Saccharomyces Cerevisiae

Liu, Zitao
Major: Anatomy and Cell Biology
Advisor: Randell Armant
Dissertation Title: Regulations of Trophoblast Differentiation During Implantation and Placentation: The Centrla Role of Intracellular Calcium as a Second Messenger and Its Transactivation of ERBB Receptor Tyrosine Kinases

Marinetti, Laureen
Major: Physiology
Advisor: Randall Commissaris
Dissertation Title: The Pharmacology of Gamma Valerolactone (GVL) as Compared to Gamma Hydroxybutrate (GHB), Gamma Butyrolactone (GBL), 1,4, Butanediol (1,4 BD), Ethanol (EtOH) and Baclofen (BAC) in the Rat

Menard, Raymond
Major: Pharmacology
Advisor: Raymond Mattingly
Dissertation Title: The Role of P21-Activated Kinase in Cell Signaling

Mitchell, Todd
Major: Cellular and Clinical Neurobiology
Advisor: Gregory Moore
Dissertation Title: Mood Stabilizers and Neuroprotection

Moosa, Mahomed-Yunus S.
Major: Immunology and Microbiology
Advisor: Robert Akins
Dissertation Title: Investgation of Virulence and Resistant Gene Expression in Candida Albicans: Studies on Primary Isolates Form Patients' with Acute Vulvovaginal Candidiasis.

Morgan, Rebecca
Major: Immunology and Microbiology
Advisor: Paul Wooley
Dissertation Title: Glucose-6-Phosphate and Joint Antigen Reactivity in Two Mouse Models of Autoimmune Arthritis

Morris, Gerald
Major: Immunology and Microbiology
Advisor: Yi-Chi Kong
Dissertation Title: Characterization of Regulartory T Cells Mediating Induced Tolerance to Experimental Autoimmune Thyroiditis

Murariu, Alina
Major: Physiology
Advisor: Jonathon Sullivan
Dissertation Title: Survival Signaling by Insulin in Early Brian Reperfusion

Nanua, Suparna
Major: Immunology and Microbiology
Advisor: Fayth Yoshimura
Dissertation Title: Elucidation of the Mechanism Involved in Oncogenic Murine Leukemia Virus Induced Apoptosis

Owen, Cheri
Major: Physiology
Advisor: Blaine White
Dissertation Title: Mechanisms Regulating Phosphorulation of the a-Subunit of Eukaryotic Initiation Factor 2 During Post-Ischemic Brain Reperfusion

Parman, Amy
Major: Cancer Biology
Advisor: George Brush
Dissertation Title: MEC1 and Replication Protein A: Biochemical and Functional Analysis of an Extraordinary Enzyme and Protein

Rhiew, Richard
Major:
Physiology
Advisor: John Phillis
Dissertation Title: Gene Expression Profiling of Chemoresistance in Human Malignant Gliomas

Rizk, Natalie
Major: Physiology
Advisor: Joseph Dunbar
Dissertation Title: Cerebral Ischemia Induced Apoptosis and Necrosis in Normal and Diabetic Rats

Rodenbaugh, David
Major: Physiology
Advisor: Stephen DiCarlo
Dissertation Title: The Influence of Paraplegia on Blood Pressure Related Cardiovascular Disease Risk Factors and the Subceptibility to Ventricular Arrhythmias

Sadidi, Mahieh
Major: Cellular and Clinical Neurobiology
Advisor: Donald Kuhn
Dissertation Title: Footprints of Neurotoxicity: Posttranslational Modication of Tyrosine Hydroxylase

Santanam, Lakshmi
Major: Medical Physics
Advisor: Jay Burmeister
Dissertation Title: Clinical Applications of IMRT to Adenocarcinoma of Prostate: Portal Dose Verification and Intensity Modulated Neutron Radiotherapy

Schober, Megan
Major: Pathology
Advisor: Yong Chen Hyeong Reh Kim
Dissertation Title: Effects of Hormonal Environment on Prostate Cancer Progression

Shaikh, Aasef
Major: Physiology
Advisor: Paul Finlayson
Dissertation Title: Pharmacological Modulation of Superior Olivary Complex Neural Excitability

Sun, Haihao
Major: Cancer Biology
Advisor: Anthony Shields
Dissertation Title: Development of the Thymidine Analogs as Positron Emission Tomography Imaging and Antineoplastic Agents

Swick, Lance
Major: Cellular and Clinical Neurobiology
Advisor: Gregory Kapatos
Dissertation Title: Discovery of Human GTP Cyclohydrolase I Protein Binding Partners

Tang, Lin
Major: Cancer Biology
Advisor: Michael Tainsky
Dissertation Title: Study of Promoter Hypermethylation Regulated Interferon Signaling Pathway in Immortalization

Wang, Jian
Major: Biochemistry and Molecular Biology
Advisor: Domenico Gatti
Dissertation Title: Structure and Function of Aquifex Aeolicus 3-Deoxy-D-Manno-Octulosonate-8-Phosphate Synthase and Protein and Ligand Dynamics in 4-Hydroxybenzoate Hydroxylase

Wang, Zhiyu
Major: Anatomy and Cell Biology
Advisor: Michelle Kurpakus-Wheater
Dissertation Title: The Effect of Hypoxia on the Urokinase Plasminogen Activator System and Cell Adhesion and Migration in Human Corneal Epithelial Cells

Wykes, Susan
Major: Molecular Biology and Genetics
Advisor: Stephen Krawetz
Dissertation Title: Dynamic Chromatin: The Organization and Regulation of Haploid-Specific Domains

Zhang, Wei
Major: Pharmacology
Advisor: Bruce Berkowitz
Dissertation Title: Retinal Oxygenation in Experimental Retinopathy of Prematurity

Zhong, Jinhui
Major: Molecular Biology and Genetics
Advisor: Russell Finley
Dissertation Title : Development of High Throughput Yeast Two-Hybrid Strategies for Proteome-Wide Protien-Protein Interaction Maps

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School of Medicine PhD Graduates
May 2003

Edwin, Samuel
Major: Physiology (Advisor: Marappa Subramanian)
Dissertation Title: Matrix Metalloproteinases in Pregnancy and Parturition


Fan, Bin
Major: Biochemistry (Advisor: Barry Rosen)
Dissertation Title: Biochemical and Functional Studies on Copa: The Escherichia Coli Cu (I)-TranslocatingP-Type Atpase


Farr, Jonathan
Major: Medical Physics (Advisor: Mark Yudelev)
Dissertation Title: A Fast Neutron Multi-Leaf collimator (MLC) for Intensity Modulated Neutron Radiotherapy (IMNRT)


LI, Jinzhu
Major: Immunology and Microbiology (Advisor: Harley Tse)
Dissertation Title: Immunological Mechanism for Initiation of Relapses of Experimental Allergic Encephalitomyelitis


Liu, Ye
Major: Biochemistry (Advisor: Vasily Studitsky)
Dissertation Title: Mechanism of Enhancer Action Over a Large Distance and Transcription Through Nucleosome by Rna Polymerase II


Lu, Lin
Major: Immunology and Microbiology (Advisor: Alan Hudson)
Dissertation Title: RSF1 and RSF2, Nuclear Genes Encoding Proteins Required for Respiratory Growth and Mitochondrial DNA Maintenance in Saccharomyces Cerevisiae


Mensah-Osman, Edith
Major: Cancer Biology (Advisor: Ramzi Mohammed)
Dissertation Title: Mechanism of DNA Damage, Cell Cycle Arrest and Apoptosis in Indolent B-Cell Lymphomas

Paramita Mukherjee
Major: Immunology and Microbiology (Advisor: Paul Wooley)
Dissertation Title: Effect of TNF-R Gene Therapy on the Reactivity of Autoimmune Lymphocytes in Collagen Induced Arthritis


Munguia, Audelia
Major: Immunology and Microbiology (Advisor: Paul Roberts)
Dissertation Title: Host Cell and Viral Determinants Involved in the Formation of Filamentous Influenza a Virus Particles

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School of Medicine PhD Graduates
Fall 2002

Ahuja, Anupama
Major: Biochemistry (Advisor: David Evans)
Dissertation Title: Pyrimidine Biosynthesis In Aquifex Aeolicus Lessons From An Ancestral Organism

Ansorge, Eric
Major: Physiology (AdvisCor: Donal O'Leary)
Dissertation Title: Muscle Metaboreflex ontrol of Coronary Blood flow and Ventricular Function

Atanaskova, Natasha
Major: Cancer Biology (Advisor: Kaladhar Reddy)
Dissertation Title: The Role of Growth Factor and Estrogen Receptor Cross-Talk in Tumor Progression

Baxa, Dwayne
Major: Immunology and Microbiology (Advisor: K.Y. Yoshimura)
Dissertation Title: The Reduction of NF-kB By Genistein In T-Cell Lymphomas Generated By Mink Cell Focus-Forming Virus

Biliran, Hector
Major: Pathology (Advisor: Shijie Sheng)
Dissertation Title: Complex Regulation of Urokinase-Type Plasminogen Activator by Tumor Suppressive Maspin

Cerghet, Mirela
Major: Anatomy and Cell Biology (Advisor: Robert Skoff)
Dissertation Title: Sexual Dimorphism of Neuroglia Cells

Chen, Gang
Major: Cancer Biology (Advisor: Zora Djuric)
Dissertation Title: 2,6-Cyclolycopene-1,5-Diol: A New Marker of Oxidative Stress

Ding, Bee Ching
Major: Pharmacology (Advisor: Larry Matherly)
Dissertation Title: Cellular and Molecular Mechanisms of the Human Reduced Folate Carrier

Garnica, Hector
Major: Medical Physics (Advisor: Frank VanDenHeuvel)
Dissertation Title: Radiation Source Modeling for Monte Carlo-Based Treatment Planning Systems

He, Tongming
Major: Medical Physics (Advisor: Frank Huevell)
Dissertation Title: Implementatoin of Amonter Carlo Based Inverse Planning Model For Clinical IMRT With MCNP Code

Liu, Xiang
Major: Cancer Biology (Advisor: Larry Matherly)
Dissertation Title: Characterization of Membrane Topology and Structural and Functional Elements of the Human Reduced Folate Carrier Protein

Pierson, Christopher
Major: Pathology (Advisor: Anders Sima)
Dissertation Title:

Pilitsis, Julie
Major: Physiology (Advisor: John Phillis)
Dissertation Title: The Effect of Stroke and Other Cerebral Insults on the Release of Free Fatty Acids

Pilon, Shari
Major: Immunology and Microbiology (Advisor: W.-Z WEI)
Dissertation Title: Anti-Tumor Immunity Induced by ERBB-2 DNA Vaccines

Shen, Jian
Major: Biochemistry and Molecular Biology (Advisor: Barry Rosen)
Dissertation Title: Nonequivalent Arsa Nucleotide Binding Site and Preliminary Studies of an Arsa Homolgue in Yeast

Wong, Marco
Major: Biochemistry and Molecular Biology (Advisor: Barry Rosen)
Dissertation Title: CADC, A Metalloregulatory Protein of the Cadmium Resistance Operon of Staphylococcus Aureus P1258

Yang, Li
Major: Molecular Biology and Genetics (Advisor: Li Li)
Dissertation Title: Study of a Novel Gene Hemogen/EDAG in Hematopoiesis and Spermatogenesis

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School of Medicine PhD Graduates
May 2002


Demchik, Lisa
Major: Cancer Biology (Adviser: Bonnie Sloane)
Dissertation Title: “Trafficking of Cathepsin B-GFP Fusion Proteins in Breast Carcinoma Cells and Cathepsin B Deficient Fibroblasts.”

Khalil,
Mohammad
Major: Cellular and Clinical Neurobiology (Adviser: Gregory Kapatos)
Dissertation Title: “The De Novo Biosynthesis of Tetrahydrobiopterin by the No-Producing Cerebellar Granule Neurons: Its Regulation by cAMP and Potential Ability to Augument Neuronal Nitric Oxide Synthase Activity.”

Krueger,
Joseph
Major: Cancer Biology (Adviser: Kaladhar Reddy)
Dissertation Title: “The Role of MAPK and PKC in Breast Cancer Progression.”

Mahadeo,
Dana
Major: Biochemistry and Molecular Biology (Adviser: Sharon Ackerman)
Dissertation Title: “A Network Model Governing Spore Formation, Dormancy, and Germination in Dictoselium Discoideum.”

Page,
Andrea
Major: Anatomy and Cell Biology (Adviser: Jose Rafols)
Dissertation Title: “Differential Phosphorylation of Eukaryotic Initiation Factor 2-Alpha in Brain Neurons Following Ischemia and Reperfusion and Its Relationship to Mitochondrial Release of Cytocrome c.”

Wesa,
Amy
Major: Cancer Biology (Adviser: Anne Galy)
Dissertation Title: “The T Cell Stimulatory Function of Dendritic Cells: Regulation by Cytokines and CD40 Ligand.”

White,
Catherine
Major: Immunology and Microbiology (Adviser: Jeffrey Hobden)
Dissertation Title: "Quorum Sensing and Virulence in Pseudomonas Aeruginosa Ocular Infection"

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Doctor of Philosophy Degrees
December 2001